— Life on Earth —

Our mission is to Explore Infectious Disease

Featuring...

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Yeasen Gentaur RNA-Rocket

Align your Illumina fastQ reads against supported genomes, view supported genomes, and estimate gene expression values using an RNA-Seq Pipeline running on Galaxy.

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Host Response Data

View Host Response proteomics and transcriptomics data collected and curated from multiple sources.

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Pathogen Interaction Gateway

Generate a network graph of Protein-Protein Interactions, including Host-Pathogen Interactions, from your custom selection of hosts/vectors, bacteria, viruses, and eukaryotic pathogens.

News & Announcements from the BRCs

Host Response Data Updated

12 Dec 2013-Pathogen Portal

Pathogen Portal BioSet pages now contain additional gene information gathered from UniProt (i.e., protein name and UniProt ID). A Gene Details page that... click to see more

10 Dec 2013-VectorBaseRelease VB-2013-12

4 Dec 2013-PATRICPATRIC Presents Workshop for Kwazulu-Natal Research Institute for Tuberculosis and HIV

25 Nov 2013-IRDNext IRD Release

25 Nov 2013-ViPRNovember 2013 ViPR Release

25 Sep 2013-EuPathDBPiroplasmaDB 4.0 Released

About the Pathogen Portal

The Pathogen Portal supports and links to five Bioinformatics Resource Centers (BRCs). Each BRC specializes in a different group of pathogens, focusing on, but not limited to, pathogens causing (Re-)Emerging Infectious Diseases, and those in the NIAID Category A-C Priority Pathogen lists for biodefense research. The scope of the BRCs also includes Invertebrate Vectors of Human Disease.

In addition to supporting, and serving as an entryway to, the BRCs, the Pathogen Portal's scientific focus is integrating host-response data that span the pathogens and vectors supported by the BRCs, thereby moving towards an integrative view of Host-Pathogen-Environment interactions, also known as the Disease Triangle. Originating from plant pathology, the concept of the Disease Triangle provides an ecological view of disease which is increasingly relevant to the Health Sciences. According to this view, disease arises when three criteria are met: an infectious Pathogen; a susceptible Host, and a conducive (to disease) Environment. Because some diseases include invertebrate Vectors as part of their ecology, the Disease Triangle broadly considers Vectors to be a component of the Environment.

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The Pathogen Portal is developed and maintained by the CyberInfrastructure Division at the Virginia Bioinformatics Institute at Virginia Tech. New data and analysis tools are added regularly.

This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272200900040C, awarded to BWS Sobral.

Bioinformatics Resource Centers for Infectious Disease.

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